Address: 3a Calle Oriente 28A, La Antigua
Antigua · Guatemala · 5-starHotel No: 2005175
Hotel Museum Spa Casa Santo Domingo
Overview.
AntiguaFind your rhythm.
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Hotel Museum Spa Casa Santo Domingo is a 5-star hotel in Antigua, Guatemala. Address: 3a Calle Oriente 28A, La Antigua.
Beyond the hotel: Antigua
Location
Hotel Museum Spa Casa Santo Domingo is a 5-star hotel in Antigua, Guatemala. Address: 3a Calle Oriente 28A, La Antigua.
- Jade Maya Factory and Museum, 0.1 km
- Las Capuchinas Monastery, 0.4 km
- Choco Museum, 0.5 km
- La Casa de los Gigantes, 0.6 km
- Central Park, 0.6 km
Facilities
- Bar(s)
- Restaurant(s)
- Room Service
Which room feels like you?
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Live availability appears here once dates and guests are set.
Choose datesThis hotel’s price over the last 30 days.
Each day, the lowest price for a one-night stay (2 adults) one month ahead.
Latest 344.01 USD
Amounts day by day
- 14 Oct 2026: 345.18 USD
- 16 Oct 2026: 340.96 USD
- 17 Oct 2026: 341.29 USD
- 18 Oct 2026: 376.25 USD
- 24 Oct 2026: 372.23 USD
- 27 Oct 2026: 372.76 USD
- 30 Oct 2026: 337.63 USD
- 31 Oct 2026: 338.82 USD
- 1 Nov 2026: 337.52 USD
- 2 Nov 2026: 335.86 USD
- 3 Nov 2026: 336.14 USD
- 4 Nov 2026: 336.16 USD
- 6 Nov 2026: 336.78 USD
- 7 Nov 2026: 338.56 USD
- 8 Nov 2026: 337.87 USD
- 9 Nov 2026: 338.02 USD
- 10 Nov 2026: 334.34 USD
- 11 Nov 2026: 344.01 USD
- Lowest
- 334.34 USD
- Highest
- 376.25 USD
- Latest
- 344.01 USD
14 October 2026 - 11 November 2026. Per night; choosing dates asks for the live price, which is the one that applies.
Dashed line: days without a price.
Spend the day your way.
Everyday comforts
Room Service
Amenities and conditions
- Bar(s)
- Restaurant(s)
- Room Service
Included and extra-charge services depend on the selected package.
What’s outside your door?
Hotel Museum Spa Casa Santo Domingo
3a Calle Oriente 28A, La Antigua
Google Maps loads when you tap.Airport distance.
22 km from La Aurora International Airport (GUA) in a straight line
104 km from Retalhuleu Airport (RER) in a straight line
What’s the weather like in Antigua?
Monthly averages
November · Antigua
23°Average high
14°Average low
Historical monthly averages, not a forecast for your travel dates. 2021–2025.
Good to know.
Early check-in / late check-outSubject to availability and confirmation
Cancellation and payment
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Taxes and local charges
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Children and accessibility
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Beyond the hotelAntigua.
Explore the city guideAntigua.
A new story every day.
Antigua Guatemala is a city in the central highlands of Guatemala, in the Sacatepéquez department, and was the country's capital in the Spanish colonial period. Its colonial architecture is a UNESCO World Heritage Site, and it is ringed by the Agua, Fuego and Acatenango volcanoes.
Antigua
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Starting priceFrom 10 January 2027, 305.16 USD per night
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